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| Food-borne botulism signs and symptoms: Vomiting Diarrhea Constipation (usually follows the diarrhea) Nausea More severe (neurological) signs and symptoms usually appear a day or two after infection. In some rare cases, according to the National Health Service (NHS) UK, more serious symptoms can appear within about six hours. Patients who have consumed a large amount of clostridium botulinum toxin may have neurological symptoms immediately. Wound botulism - the incubation period in this case is from 4 days to a couple of weeks. The nerves that connect the brain to the spine (cranial nerves) experience the first symptoms, and then spread to the rest of the body. Neurological signs and symptoms of both food-borne and wound botulism are identical, although the wound botulism ones may take longer to appear. The patient may experience double vision, the eyelids may droop, there will be facial weakness, a dry mouth, dysphagia (swallowing difficulties) and speech defects (slurring). 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Infant botulism signs and symptoms may include: Constipation (first sign) Bad temper Excessive drooling when feeding Eyelids sag Facial expression is flat Lethargy, listlessness Respiratory difficulties Slow or improper reflexes The baby cries weakly The child feels floppy The infant does not gag Unfocused eyes Weak sucking (baby) What are the causes of botulism? Botulism is caused by botulinum toxin, a poison produced by the bacterium Clostridium botulinum. The organism is common in the soil and exists in untreated water, and can survive in this environment as a resistant spore. Clostridium botulinum produces spores that can survive in poorly preserved or canned foods, where they produce a toxin. When consumed even extremely tiny amounts of the toxin can cause severe poisoning. The most commonly tainted foods are home-canned vegetables, cured pork and ham, raw fish, smoked fish, honey and corn syrup. The organism can also enter an open wound and produce toxins within the wound. 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